Search on: LEUKOTRIENE B4 
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Descriptor English:   Leukotriene B4 
Descriptor Spanish:   Leucotrieno B4 
Descriptor Portuguese:   Leucotrieno B4 
Synonyms English:   LTB4
5,12-diHETE
5,12-HETE  
Tree Number:   D10.251.355.255.100.450.411
D23.469.050.175.450.415
Definition English:   The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990) 
Indexing Annotation English:   /biosyn /physiol permitted; DF: note short X ref
History Note English:   94; was LEUKOTRIENES B 1983-93; LEUKOTRIENE B4 was see LEUKOTRIENES B 1983-93 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   31746 
Unique Identifier:   D007975 

Occurrence in VHL:
 

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